Topical agents in burn care

Activity of topical antimicrobial agents against multidrug-resistant bacteria recovered from burn patients.

BACKGROUND Topical antimicrobials are employed for prophylaxis and treatment of burn wound infections despite no established susceptibility breakpoints, which are becoming vital in an era of multidrug-resistant (MDR) bacteria. We compared two methods of determining topical antimicrobial susceptibilities. METHODS Isolates of Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus (...

Advances in burn care.

PURPOSE OF REVIEW This article reviews and critiques new developments in the critical care of burn patients. RECENT FINDINGS The practice of restrictive transfusion is slowly gaining traction. Abdominal compartment syndrome is associated with resuscitation volumes of 300 ml/kg per 24 h, and percutaneous decompression may be a treatment option. Adrenal insufficiency is common, but whom and whe...

History of burn care. A survey of important changes in the topical treatment of thermal injuries.

INTRODUCTION THE routine successful treatment of major burns is a very recent development in medical history. For example, as late as 1939 it was widely thought that a person with burns over one-third of the body could not survive, while today we routinely treat 65 per cent and greater total body surface area burns with very high confidence of success. Much of our present-day success is obvious...

Topical antibacterial agents.

Topical antibacterial agents occupy an important niche of antimicrobial therapy for both inpatients and outpatients. These agents, including antiseptic and antibiotic preparations, are used for prophylaxis and treatment of infection. Prophylactic uses include application for traumatic and surgical wounds, burns, intravascular catheters, and eradication of S. aureus nasal carriage. Topical antib...

Burn care in South Africa.